Table S6 The use of Venn
analysis to identify photoreceptor-enriched and retinal disease genes This lists all the number of tags in each Venn category, the number of known photoreceptor-enriched genes in each category, the number of genes shown in this study to be photoreceptor-enriched, the number shown by this study or previously shown to not be photoreceptor-enriched, the number not tested by in situ, and the number of tags that did not match any predicted gene or EST. |
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Breakdown of tags by Venn category | ||||||
Tags in category | Known PR-enriched | Novel PR-enriched | Not PR-enriched | Not tested | Unknowns | |
4 out of 4 | 91 | 28 | 40 | 2 | 3 | 18 |
3 out of 4 | 81 | 23 | 46 | 4 | 0 | 8 |
2 out of 4 | 315 | 11 | 82 | 29 | 157 | 36 |
1 out of 4 | 417 | 1 | 23 | 18 | 360 | 15 |
0 out of 4 | 214 | 1 | 7 | 8 | 189 | 9 |
This lists the known photoreceptor-enriched genes and their frequency of being disease genes as a percentage of all known photoreceptor-enriched genes identifed by Venn criteria. | ||||||
Known PR-enriched tags | Known disease genes tags | Disease genes/known genes | ||||
4 out of 4 | 28 | 21 | 75% | |||
3 out of 4 | 23 | 21 | 91% | |||
2 out of 4 | 11 | 4 | 36% | |||
1 out of 4 | 1 | 1 | 100% | |||
0 out of 4 | 1 | 0 | 0% | |||
Detection of known photoreceptor-enriched retinal disease genes by the Venn criteria. Tags detected at low abundance were present at less than 0.01% of total transcripts. | ||||||
Total photoreceptor-enriched cloned disease genes | 35 | |||||
Total 4 of 4 | 12 | 34% | ||||
Total 3 of 4 | 8 | 23% | ||||
Total 2 of 4 | 3 | 9% | ||||
Total 1 of 4 | 1 | 3% | ||||
Total identified | 24 | 69% | ||||
Detected/low abundance | 4 | 11% | ||||
Cone-specific | 2 | 6% | ||||
Not detected | 6 | 17% | ||||
No mouse ortholog | 3 | 9% |