Table S6 The use of Venn analysis to identify photoreceptor-enriched and retinal disease genes
This lists all the number of tags in each Venn category, the number of known photoreceptor-enriched genes in each category, the number of genes shown in this study to be photoreceptor-enriched, the number shown by this study or previously shown to not be photoreceptor-enriched, the number not tested by in situ, and the number of tags that did not match any predicted gene or EST.
Breakdown of tags by Venn category
Tags in category Known PR-enriched Novel PR-enriched Not PR-enriched Not tested Unknowns
4 out of 4 91 28 40 2 3 18
3 out of 4 81 23 46 4 0 8
2 out of 4 315 11 82 29 157 36
1 out of 4 417 1 23 18 360 15
0 out of 4 214 1 7 8 189 9
This lists the known photoreceptor-enriched genes and their frequency of being disease genes as a percentage of all known photoreceptor-enriched genes identifed by Venn criteria.
Known PR-enriched tags Known disease genes tags Disease genes/known genes
4 out of 4 28 21 75%
3 out of 4 23 21 91%
2 out of 4 11 4 36%
1 out of 4 1 1 100%
0 out of 4 1 0 0%
Detection of known photoreceptor-enriched retinal disease genes by the Venn criteria.  Tags detected at low abundance were present at less than 0.01% of total transcripts.
Total photoreceptor-enriched cloned disease genes 35
Total 4 of 4 12 34%
Total 3 of 4 8 23%
Total 2 of 4 3 9%
Total 1 of 4 1 3%
Total identified 24 69%
Detected/low abundance 4 11%
Cone-specific 2 6%
Not detected 6 17%
No mouse ortholog 3 9%